GONADOTROPHIN RESPONSES TO GnRH IN PRECOCIOUS PUBERTY TREATED WITH GnRH ANALOGUE
نویسندگان
چکیده
منابع مشابه
Evaluating the Efficacy of Treatment with a GnRH Analogue in Patients with Central Precocious Puberty
Objective. GnRH analogues (GnRHa) are used in the treatment of central precocious puberty (CPP). The purpose of this study was to evaluate the efficacy of treatment with a GnRHa (leuprolide acetate) in patients with CPP. Subjects and Methods. A total of 62 female child patients who had been diagnosed with CPP, rapidly progressive precocious puberty (RP-PP), or advanced puberty (AP) and started ...
متن کاملHormonal changes during GnRH analogue therapy in children with central precocious puberty.
Gonadotropin releasing hormone analogues (GnRHa) have been used for treatment of central precocious puberty (CPP) for more than 15 years. They are generally considered safe although data on potential long-term side effects are scarce. However, GnRHa therapy has profound effects on both the hypothalamopituitary-gonadal axis as well as on growth hormone (GH) secretion. Gonadal activity is increas...
متن کاملReversible inhibition of central precocious puberty with a long acting GnRH analogue.
A 7 year old girl with precocious puberty was treated with buserelin, a long acting analogue of gonadotrophin releasing hormone. Spontaneous and stimulated gonadotrophin secretion became prepubertal but returned to pubertal values when buserelin was withdrawn, suggesting that normal sexual maturation should follow cessation of treatment.
متن کاملEvaluation of central precocious puberty treatment with GnRH analogue at the Triangulo Mineiro Federal University (UFTM).
OBJECTIVE To report our experience of treating central precocious puberty (CPP) with a GnRH analogue with respect to the final heights (FH) attained in patients who completed treatment. SUBJECTS AND METHODS Among 105 records of children diagnosed with precocious puberty, 62 cases (54 girls and 8 boys), who were treated with leuprolide acetate/3.75 mg/monthly, were selected, and divided into 4...
متن کاملWeight evolution in girls treated for idiopathic central precocious puberty with GnRH analogues.
UNLABELLED Data concerning the effects of GnRHa on weight gain are scarce. OBJECTIVE To assess the variation of the body mass index (BMI) in girls during GnRHa treatment for idiopathic central precocious puberty (CPP). PATIENTS AND METHODS Semestral anthropometric data from 176 girls treated with goserelin or leuprorelin were analyzed. RESULTS BMI z-score increased from 1.5 +/- 0.1 SD bef...
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ژورنال
عنوان ژورنال: Clinical Endocrinology
سال: 1985
ISSN: 0300-0664,1365-2265
DOI: 10.1111/j.1365-2265.1985.tb01087.x